| 摘要 |
<p>The DNA encoding novel peptides isolated from the blowfly Calliphora vomitoria of the callatostatin class of insect neuropeptides has been isolated. The DNA which encodes these novel peptides also encodes the other known Leucallatostatin peptides that have already been isolated from C. vomitoria. The homologues of this gene have also been isolated from Helicoverpa armigera and the Australian sheep blowfly Lucilia cuprina. The peptides have inhibitory effects on gut motility in the blowfly C. vomitoria and may have allatostatic effects in cockroaches. The peptides have application as insecticides and the DNA encoding the peptides may be inserted into a baculovirus for use as an insecticide against the pest species Cydia pomonella or Helicoverpa armigera, or other target organisms. Variants of these peptides have also been isolated from Cydia pomonella, Helicoverpa armigera and Pteronida salicis.</p> |
