发明名称 Iron complexes of nitrogen-containing macrocyclic ligands effective as catalysts for dismutating superoxide
摘要 Pharmaceutical compositions of low molecular weight mimics of superoxide dismutase (SOD) represented by formula (I), wherein R, R', R1, R'1, R2, R'2, R3, R'3, R4, R'4, R5, R'5, R6, R'6, R7, R'7, R8, R'8, R9, and R'9, and X, Y, Z and n are as defined herein, useful as therapeutic agents for inflammatory disease states and disorders, ischemic/reperfusion injury, stroke, atherosclerosis, inflammatory bowel disease and all other conditions of oxidant-induced tissue damage or injury.
申请公布号 AU2065697(A) 申请公布日期 1997.10.01
申请号 AU19970020656 申请日期 1997.03.11
申请人 G.D. SEARLE & CO. 发明人 DENNIS P. RILEY
分类号 C07D259/00;A61K31/00;A61K31/555;A61P1/00;A61P9/00;A61P9/10;A61P43/00;C07F15/02;C12Q1/02 主分类号 C07D259/00
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