发明名称 |
SUSTAINED-RELEASE GRANULAR PREPARATION AND PROCESS FOR PRODUCING THE SAME |
摘要 |
<p>This invention relates to sustained-release granular preparations obtained by wet-granulating an aqueous suspension, which comprises a medicinal ingredient, a fine particulate polymer having an average particle size not greater than 50 mu m and a plasticizer, into granules and treating said granules at a temperature not less than the lower one of a minimum film-forming temperature and glass transition temperature of a mixture of said polymer and said plasticizer. This invention is also concerned with a process for the production of the sustained-release granular preparations. According to the present invention, granular preparations having an excellent sustained-release property and a high safety to the human body can be easily produced in a simple manner.</p> |
申请公布号 |
EP0797987(A1) |
申请公布日期 |
1997.10.01 |
申请号 |
EP19950940461 |
申请日期 |
1995.12.18 |
申请人 |
DAIICHI PHARMACEUTICAL CO., LTD. |
发明人 |
NAKAGAMI, HIROAKI;KOJIMA, MASAZUMI;SAGASAKI, SHINJI |
分类号 |
A61K9/16;(IPC1-7):A61K9/16;A61K47/38 |
主分类号 |
A61K9/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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