Cyclic (hetero)acetals of nitro substituted benzaldehydes having anti-cancer activity

摘要

New compounds having the general formula I wherein Y may be H or D; and A is H, D, alkyl with 1-4 C-atoms, halogen, nitro, amino, monoalkyl amino or dialkyl amino wherein the alkylgroups have 1-4 C atoms or OR wherein R is H or alkyl of 1-4 C-atoms; X1 and X2 may together with the carbon atom to which they are bound form a cyclic acetal, thioacetal, dithiane, aminal, oxazolidine or thiazolidine; or pharmaceutically acceptable salts thereof. The compounds are useful as anti-cancer agents.