| 摘要 |
A method of controlling male fertility in warm-blooded male animals comprising administering to male warm-blooded animals an amount of a compound selected from the group consisting of a compound of the formula <IMAGE> I wherein R1 and R2 are taken together with the nitrogen to form a saturated 5 to 6 ring heterocycle, optionally containing a second nitrogen or oxygen in the ring, R3 is alpha - or beta -methyl, n is an integer from 2 to 10, R4 and R5 together are =0 or R4 is selected from the group consisting of hydrogen, -OH and acyloxy of an organic carboxylic acid of up to 12 carbon atoms and R5 is selected from the group consisting of hydrogen, -OH, acyloxy of an organic carboxylic acid of up to 12 carbon atoms and alkyl, alkenyl and alkynyl of up to 8 carbon atoms, R6 and R7 together are =0 or are individually selected from the group consisting of hydrogen, -OH and acyloxy of an organic carboxylic acid of up to 12 carbon atoms or R5 and R6 form a double bond and R4 and R7 are hydrogen and their non-toxic, pharmaceutically, acceptable acid addition salts in an amount sufficient to control male fertility.
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