Diagnostisk markör

摘要

A diagnostic marker containing (a) a detection system such as an antibody and (b) a fluorescent functional group that is bound to the detection system and represented by the following formula: <CHEM> wherein R<1> and R<2> independently represent hydrogen atom, an alkyl group or the like; R<3> represents an alkyl group, a sulfonic acid-alkyl group or the like; X<-> represents an anion species, if required; Y represents a C1-C10 alkylene group or a C1-C10 alkylene group containing one or more atoms selected from the group consisting of oxygen atom, nitrogen atom and sulfur atom. The diagnostic marker emits fluorescence having a wavelength of 780 nm or more when irradiated with near or far infrared rays, and thus useful for infrared endoscopic diagnosis or identification of a focus in surgical operation.