发明名称 METHOD FOR FLUORODE CARBOXYLATION
摘要 The present invention is directed to a method for replacing a carboxylic acid group with a fluorine group in a halogenated aliphatic carboxylic acid compound having the formula, R-COOH, to prepare a fluorinated product having the formula, R-F, wherein R is a halogenated aliphatic group including straight- and branched-chain aliphatic groups selected from the group consisting of halogenated aliphatic and halogenated alkoxy-substituted aliphatic groups, wherein the method comprises the steps of (a) reacting the halogenated aliphatic carboxylic acid compound with bromine trifluoride, and (b) recovering the fluorinated product.
申请公布号 CA2027522(C) 申请公布日期 1997.09.30
申请号 CA19902027522 申请日期 1990.10.12
申请人 ZENECA PHARMA INC. 发明人 HALPERN, DONALD F.;ROBIN, MARK L.
分类号 C07B39/00;C07C17/12;C07C17/363;C07C19/08;C07C41/22;C07C43/12;C07C51/367;C07C59/315;(IPC1-7):C07C41/01 主分类号 C07B39/00
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