| 摘要 |
A portable osmotic pump, having two pouches (4,3) in pressure-transmitting relationship, the first (4) containing a pumped fluid, such as infusate (5), and the second (3), a driving fluid (36). The driving fluid is created and pressurized by activation of an osmotic pump, and the rate of infusion is controlled by a semipermeable membrane (10). Activation can be by rupturing a seal (11) or by opening a closed tube (58) to permit permeant (2) to contact the semipermeable membrane. Pulses of the pumped fluid can be achieved by delivery pulses of the permeant to the second pouch. The pouches can be designed to resist collapse of the first pouch by external forces on the pumped liquid, such as gravity, movement of the first pouch and negative pressures applied to the pumped liquid. The infusate pouch is manufactured separately and can be stored apart from the rest of the system.
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