发明名称 COMPOSITE GEL MICROPARTICLES AS ACTIVE PRINCIPLE CARRIERS
摘要 Carriers for delivering medicinal, nutritional, plant-protecting or cosmetic active principles are disclosed. One of the essential aims is to provide biocompatible, biodegradable, non-immunogenic, stable, solvent-free active principle delivery particles with a controllably and adjustably small particle size for protecting the active principles without denaturing same as well as releasing said active principles. Therefore, microparticles with a cohesive structure made of a composite, physically and chemically stable and integral gel are provided which include an oil (I), e.g. coconut oil, an aqueous phase (II) and a non-cross-linked linear copolyaminoacid such as (statistical or diblock) Leu/Glu. The size of said delivery particles is controllable and adjustable between 0.05 and 500 .mu.. Said carriers are useful for delivering drugs, nutrients and plant-protecting or cosmetic substances.
申请公布号 CA2249274(A1) 申请公布日期 1997.09.25
申请号 CA19972249274 申请日期 1997.03.14
申请人 FLAMEL TECHNOLOGIES 发明人 HUILLE, SYLVAIN;LEMERCIER, ALAIN;MEYRUEIX, REMI;SOULA, GERARD
分类号 A23L1/00;A61K8/02;A61K8/31;A61K8/37;A61K8/44;A61K8/64;A61K8/73;A61K8/89;A61K8/891;A61K8/92;A61K8/97;A61K9/16;A61K9/50;A61K9/51;A61K31/70;A61K38/00;A61K38/21;A61K38/28;A61K38/43;C07H3/00;C07H21/02;C07H21/04;C08B37/10;C08L83/04;(IPC1-7):A61K9/16;A01N25/26 主分类号 A23L1/00
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