| 发明名称 |
PURIFICATION OF PHARMACEUTICAL-GRADE PLASMID DNA |
| 摘要 |
The invention is directed to a process for purifying double-stranded DNA, comprising using ceramic hydroxyapatite column chromatography. The invention is also directed to a purified recombinant plasmid DNA composition, comprising a chromosomal DNA content that is less than or equal to 0.01% as well as to a composition comprising DNA prepared by the foregoing process. |
| 申请公布号 |
WO9735002(A1) |
申请公布日期 |
1997.09.25 |
| 申请号 |
WO1997FR00472 |
申请日期 |
1997.03.17 |
| 申请人 |
RHONE-POULENC RORER S.A.;WILS, PIERRE;OLLIVIER, MONIQUE |
发明人 |
WILS, PIERRE;OLLIVIER, MONIQUE |
| 分类号 |
C12N15/09;A61K31/00;A61K31/70;A61K31/7088;A61K48/00;A61P43/00;C12N15/10;C12Q1/68 |
主分类号 |
C12N15/09 |
| 代理机构 |
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代理人 |
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