| 摘要 |
PURPOSE:To produce squalene simply and efficiently even in the case of using a raw material having low a squalene content which has not been effectively used. CONSTITUTION:Candida famata US-238 (FERM P-13,974) is cultured in a medium comprising fats and oils containing squalene as a carbon source, concentration of squalene in the medium is raised and squalene is purified and recovered. When 0.1-1vol. (w/V) % of one or more additives selected from the group consisting of calcium carbonate, calcium hydroxide, potassium carbonate and magnesium carbonate is added to the medium and the fungus is cultured, concentration of squalene in the medium is raised. |
