发明名称 |
Amino acid derivatives |
摘要 |
N-Acyl- alpha -aminocarboxylic acid derivatives of the formula <IMAGE> I wherein L, R' to R''' and Q have the definitions given in the specification, are for the treatment or prophylaxis of illnesses which are caused by the binding of adhesive proteins to blood platelets, by blood platelet aggregation and cell-cell adhesion. They are manufactured by cleaving off protecting groups in corresponding protected compounds or by converting the cyano group into the amidino group in corresponding nitriles.
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申请公布号 |
US5670515(A) |
申请公布日期 |
1997.09.23 |
申请号 |
US19950452616 |
申请日期 |
1995.05.25 |
申请人 |
HOFFMANN-LA ROCHE INC. |
发明人 |
ALIG, LEO;HADVARY, PAUL;HUERZELER, MARIANNE;MUELLER, MARCEL;STEINER, BEAT;WELLER, THOMAS |
分类号 |
A61K31/155;A61K;A61K31/165;A61K31/195;A61K31/198;A61K31/445;A61K31/451;A61P7/02;A61P7/04;C07C227/00;C07C229/00;C07C229/10;C07C233/76;C07C237/22;C07C257/18;C07C279/18;C07D;C07D207/08;C07D207/12;C07D207/16;C07D211/22;C07D211/40;C07D211/42;C07D211/44;C07D211/46;C07D211/48;C07D211/52;C07D401/06;C07D401/12;C07D451/06;C07D453/06;(IPC1-7):A61K31/44;C07D451/10;C07D451/12 |
主分类号 |
A61K31/155 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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