发明名称 Reiterative method for screening combinatorial libraries
摘要 Libraries of compounds such as nucleic acids or peptides are contacted with a target molecule and libraries that have at least one compound that bind with at least a minimum activity are determined by a reiterative process in which a change in the rate of recovery (elimination) of compounds that bind to the target indicates that the library contains such a compound. The procedure may also be used to determine indirectly the sequence of such compound by employing sublibraries, each of which have a known entity at a known position of the compound.
申请公布号 US5670326(A) 申请公布日期 1997.09.23
申请号 US19950477472 申请日期 1995.06.07
申请人 PHARMAGENICS, INC. 发明人 BEUTEL, BRUCE A.
分类号 G01N33/53;C07H21/00;C07K1/04;C07K1/22;C12Q1/68;G01N33/566;(IPC1-7):G01N33/53;G01N33/543 主分类号 G01N33/53
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