| 摘要 |
Pyrrolidone derivatives represented by general formula (I), having a neural differentiation induction effect, and hence being useful as remedies for nervous diseases, especially as an antitumor agent, a nootropic agent, an immunosuppressive agent, and an apoptosis inhibitor, and a tissue recovery agent for postoperative medication, etc., wherein R<1> represents C1-3 alkyl or is bonded to R<2> to thereby form methylidene; R<2> represents hydroxy, C1-20 alkoxy, or C1-10 alkoxy substituted by nitrooxy or phenyl; R<3> represents hydrogen or C1-20 alkyl; and R<4> represents cyano, C1-3 alkoxycarbonyl, or C2-10 alkanoyl optionally substituted by hydroxy. |
