发明名称 |
NUCLEIC ACIDS AND POLYPEPTIDES OF GROUP I SIGMA SUBUNITS OF MYCOBACTERIUM TUBERCULOSIS RNA POLYMERASE AND THEIR USE |
摘要 |
<p>The present invention provides novel nucleic acid molecules coding for sigma subunits of Mycobacterium tuberculosis RNA polymerase. It also relates to polypeptides, referred to as SigA and SigB, encoded by such nucleic acid molecules, as well as to vectors and host cells transformed with the said nucleic acid molecules. The invention further provides screening assays for compounds which inhibit the interaction between a sigma subunit and a core RNA polymerase.</p> |
申请公布号 |
NZ286081(A) |
申请公布日期 |
1997.09.22 |
申请号 |
NZ19960286081 |
申请日期 |
1996.02.27 |
申请人 |
ASTRA AG |
发明人 |
BALGANESH, MEENAKSHI;SHARMA, UMENDER |
分类号 |
A61K38/00;C07K14/35;C12N9/12;C12N15/31;(IPC1-7):C07K14/35;C12N15/63;C12P21/00;C12P21/02;C12Q1/25;G01N33/577;C12N5/10 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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