发明名称 |
Recombinant constructs encoding t cell receptors specific for human hla-restricted tumor antigens |
摘要 |
Methods are described to obtain nucleic acid molecules that encode T cell receptors and their derivatives that are human HLA-restricted and which are specific for tumor-associated antigens found in human tumors. These nucleic acids are useful in preparing recombinant cells for diagnosis and therapy of human tumors. |
申请公布号 |
AU2199797(A) |
申请公布日期 |
1997.09.22 |
申请号 |
AU19970021997 |
申请日期 |
1997.03.05 |
申请人 |
THE SCRIPPS RESEARCH INSTITUTE |
发明人 |
LINDA A SHERMAN;JOSEPH LUSTGARTEN |
分类号 |
C12N15/09;A61K31/00;A61K35/14;A61K48/00;A61P35/00;A61P43/00;C07K14/725;C12N5/10;C12P21/02;C12Q1/68;C12R1/91 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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