4-THIA-1-AZABICYCLO/3.2.0/HEPTANE-3-IMINO-2-ISOPROPYLIDENE-7-OXO ANALOGONS OF BETA-LACTAMS, PROCESSES FOR THEIR PREPARATION AND THE USE THEREOF

摘要

4-Thia-1-azabicyclo¢3.2.0!heptane-3-imino-2-isopropylidene-7-oxo Analogons of beta-Lactams, Processes for Their Preparation and the Use Thereof The object of the present invention are 4-thia-1-azabicyclo¢3.2.0!heptane-3-imino-2-isopropylidene-7-oxo beta-lactamic analogons of general formula I (see fig. I) wherein the radicals have the following meanings: R1 is hydrogen or halogen, R2 is hydrogen, halogen, phtalimide, R3 is hydrogen, alkyl, benzyl, heterocycle e.g. isoxazole, pyrazole etc. These compounds are useful as intermediates in the preparation of novelbeta-lactamic analogons or of active substances in preparations for antimicrobial therapy.