| 摘要 |
<p>An excellent ocular tension lowering agent and/or a glaucoma therapeutic agent for eye drops containing a compound shown below, salt thereof and/or ester thereof. <CHEM> ÄR<1>: Alkyl, alkenyl, a group of a formula R<5>-A-B- (R<5>: H, alkyl, cycloalkyl, acyl; A: O, S; B: Single bond, alkylene); R<2>: Alkyl, alkenyl, a group of a formula -C(R<6>)(R<7>)(R<8>> (R<6>: OH, alkoxy; R<7>, R<8>: H, alkyl, alkenyl, alkynyl, cycloalkyl, aryl, aralkyl); R<3>: COOH, a group of a formula -CON(R<9>)(R<10>> (R<9>, R<10>: H, optionally substituted alkyl); R<4>: COOH, COCOOH, tetrazoleÜ</p> |
