TGF-beta regulating substance for treatment of myopia or hyperopia

摘要

Use of a TGF- beta regulating substance for the production of an axial length control agent. More particularly, use of a TGF- beta activator, specifically a plasminogen activator, for the production of an axial elongation inhibitor or an agent for the prophylaxis and treatment of myopia. Use of a TGF- beta activation inhibitor, particularly a plasminogen activator inhibitor, for the production of an axial elongation agent or an agent for the prophylaxis and treatment of hyperopia. According to the present invention, the elongation and reduction of axial length are possible and the present invention is extremely useful for the prophylaxis and treatment of myopia or hyperopia. It is also useful for preparing experimental model animals having eyes with complete axial myopia or hyperopia exclusive of refractive myopia or hyperopia.