发明名称 PREPARATION FOR EXTERNAL USE FOR SKIN
摘要 PROBLEM TO BE SOLVED: To obtain a preparation for external use for the skin having excellent effect on skin whitening and color fading after pigmentation due to suntan, freckles and chloasma, etc., through suppressing melanogenesis, and also high in safety. SOLUTION: This preparation for external use for the skin contains 0.005-20wt.% of a compound of formula I (R is formula II or formula III). The compound of formula I, which has melanogenesis-suppressive effect and tyrosinase-inhibitory effect, is known as a precursor ofγ-irone andα-irone, each being a perfume ingredient. Of the compounds of formula I, the compound where R is formula II is named as iriflorental, while the compound where R is formula III iripallidal. These compounds can be obtained by subjecting an Iridaceae plant, especially Iris florentina of the family Iridaceae to extraction with a solvent followed by partition and purification of the resultant extract.
申请公布号 JPH09241154(A) 申请公布日期 1997.09.16
申请号 JP19960079602 申请日期 1996.03.07
申请人 SHISEIDO CO LTD 发明人 YOKOGAWA YOSHIHIRO;TANAKA NAOMI;YAGI EIICHIRO
分类号 A61K8/30;A61K8/00;A61K8/35;A61K31/015;A61K31/11;A61P17/00;A61P43/00;A61Q1/00;A61Q1/02;A61Q1/12;A61Q19/02;C07C47/267;(IPC1-7):A61K31/015;A61K7/02;A61K7/00 主分类号 A61K8/30
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