发明名称 |
Skin substitute |
摘要 |
The invention concerns a skin substitute composed of a dermis equivalent covered with an epidermis equivalent. The dermis equivalent is a film formed from a type I collagen gel containing fibroblasts. The epidermis equivalent incorporates a basal membrane equivalent, basal layer cells, in a palisade arrangement attached to the membrane equivalent by hemidesmosomes, cells of the suprabasal layers, granular cells, and flat, keratinized cells arranged near the free surface.
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申请公布号 |
US5667961(A) |
申请公布日期 |
1997.09.16 |
申请号 |
US19950471359 |
申请日期 |
1995.06.06 |
申请人 |
CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIGUES GALDERMA (CIRD GALDERMA) |
发明人 |
BERNARD, BRUNO;LENOIR, MARIE-CECILE;SHROOT, BRAHAM;DARMON, YVES-MICHEL;ASSELINEAU, DANIEL |
分类号 |
A61F2/00;A61F2/10;A61K35/12;A61L27/00;A61L27/24;A61L27/60;C12N5/02;C12N5/071;(IPC1-7):A01N1/02;C12N5/06 |
主分类号 |
A61F2/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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