| 摘要 |
PROBLEM TO BE SOLVED: To obtain a sebum secretion depressor capable of exhibiting a suppressing or preventing effect on local accumulation of fat and improving a beauty appearance of the skin by using a specific compound obtained from escin in the extract of the seed of Aesculus hippocastanum as an active component. SOLUTION: This sebum secretion depressor contains escinol or its salt expressed by the formula (R<1> is H or OH; R<2> is a pyranol residue) as an active component. Escinol is a triterpenoid-based saponin obtained by alkali- decomposition of escin in an extract of a seed of Aesculus turbinata and removing an acyl group, e.g. R<2> of OH and R<2> of β-D-glucopyranose, R<1> of OH and R<2> of β-D-xylopyranose, and R<1> of H and R<2> of β-D-galactopyranose are exemplified. Preferably, a containing amount of the escinol or its salt in this depressor is about 0.001-20wt.%, especially 0.1-7wt.% based on the total amount. The preparation for external use has an effect on seborrheric disease such as a pimple induced by hypersecretion of sebum and a seborrherric handruff. |
