摘要 |
An ion exchanger for chromatographic separation has the structure P-S-A, wherein P is an insoluble support, S is a spacer, and A is a functional ligand. According to the invention the functional ligand A comprises two positively charged atoms, each selected from nitrogen and sulphur, at a distance of two atoms from each other, with the proviso that A can not be 4-methyl-1,4-diazabicyclo[2.2.2]octan-1-yl, 1,4,4-trimethylpiperazinium-1-yl, 1,4-dimethyl-1,4-diazabicyclo[2.2.2]octan-2-yl or 1,1,4,4,4-pentamethyl-1,4-diazabutan-1-yl. |