发明名称 |
2-THIOXOTETRAHYDROPYRIMIDIN-4-ONE DERIVATIVES |
摘要 |
This invention relates to the use of 2-thioxotetrahydropyrimidin-4-one derivatives to increase HDL cholesterol concentration and as therapeutic compositions for treating atherosclerotic conditions such as dyslipoproteinemias and coronary heart disease. The compounds of this invention are represented by formula (a), wherein: R is C1-C6 alkyl or C2-C6 alkenyl; and R<1>, R<2>, and R<3> are independently hydrogen, halogen or lower alkyl. |
申请公布号 |
WO9732855(A1) |
申请公布日期 |
1997.09.12 |
申请号 |
WO1997US02281 |
申请日期 |
1997.02.12 |
申请人 |
AMERICAN HOME PRODUCTS CORPORATION |
发明人 |
CHAI, SIE-YEARL;ELOKDAH, HASSAN, MAHMOUD;SULKOWSKI, THEODORE, SYLVESTER |
分类号 |
A61K31/00;A61K31/505;A61P9/00;A61P9/10;C07D239/22 |
主分类号 |
A61K31/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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