Polynucleotides and polypeptides in pathogenic mycrobacteria and their use as diagnostics, vaccines and targets for chemotherapy
摘要
PCT No. PCT/GB96/03221 Sec. 371 Date Sep. 16, 1998 Sec. 102(e) Date Sep. 16, 1998 PCT Filed Dec. 23, 1996 PCT Pub. No. WO97/23624 PCT Pub. Date Jul. 3, 1997The invention provides a nucleotide sequence representing a pathogenicity island found in species of pathogenic mycobacteria. The islands are shown as SEQ ID NOs: 3 and 4 and comprises several open reading frames encoding polypeptides. These polypeptides and their use in diagnosis and therapy form a further aspect of the invention.
申请公布号
WO9723624(A3)
申请公布日期
1997.09.12
申请号
WO1996GB03221
申请日期
1996.12.23
申请人
ST. GEORGE'S HOSPITAL MEDICAL SCHOOL;HERMON-TAYLOR, JOHN;DORAN, TIM;MILLAR, DOUGLAS;TIZARD, MARK;LOUGHLIN, MARK;SUMAR, NAZIRA;FORD, JOHN
发明人
HERMON-TAYLOR, JOHN;DORAN, TIM;MILLAR, DOUGLAS;TIZARD, MARK;LOUGHLIN, MARK;SUMAR, NAZIRA;FORD, JOHN