发明名称 COMBINATIONS OF FUNGAL CELL WALL DEGRADING ENZYME AND FUNGAL CELL MEMBRANE AFFECTING COMPOUND
摘要 <p>A system for inhibiting the germination or growth of a fungus comprises (a) fungal cell wall degrading chitinolytic or glucanolytic enzyme and (b) antifungal cell membrane affecting compound. Exemplified antifungal fungal cell membrane affecting compounds include flusilazole, miconazole, osmotin, gramicidin, valinomycin, phospholipase B, and trichorzianines. The system components (a) and (b) may be supplemented with polyene macrolide antibiotic, antifungal epithiodiketopiperazine antibiotic (e.g., gliotoxin), fungal cell wall biosynthesis inhibitor (e.g., L-sorbose) and/or detergent. Embodiments include method of contacting a plan which expresses cell wall degrading enzyme with antifungal fungal cell membrane affecting compound.</p>
申请公布号 WO1997032973(A1) 申请公布日期 1997.09.12
申请号 US1997003344 申请日期 1997.03.05
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