发明名称 |
PROCESS FOR THE PREPARATION OF N< omega >-TRIFLUOROACETYLATED BASIC AMINO ACIDS |
摘要 |
A process for preparing an N< omega >-trifluoroacetylated basic amino acid from a basic amino acid and a trifluoroacetic acid ester, characterized by gradually adding a trifluoroacetic acid ester to an aqueous basic solution containing a basic amino acid in a concentration of about 5 to 40 % (w/v) based on the volume of the solvent charged and a basic pH regulator while keeping the aqueous solution at a pH of 10.6 to 11.4 and a temperature of 20 DEG C or below to conduct a reaction, making the formed N< omega >-trifluoroacetylated basic amino acid crystallize out of the resulting aqueous solution, and separating the amino acid therefrom.
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申请公布号 |
WO9732841(A1) |
申请公布日期 |
1997.09.12 |
申请号 |
WO1997JP00690 |
申请日期 |
1997.03.06 |
申请人 |
KANEKA CORPORATION |
发明人 |
UEDA, YASUYOSHI;MANABE, HAJIME;MITSUDA, MASARU |
分类号 |
C07C231/02;C07C231/24;(IPC1-7):C07C233/47 |
主分类号 |
C07C231/02 |
代理机构 |
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代理人 |
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地址 |
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