| 摘要 |
<p>A cyclic lipopeptide acylase which can effectively remove an acyl side chain from a cyclic lipopeptide, specifically FR901379 represented by general formula (I) or an analogue thereof; and a process for the preparation of a cyclic peptide with the acylase, wherein R1 is acyl, R2 is hydroxy or acyloxy, R3 is hydrogen or hydroxy, R4 is hydrogen or hydroxy, R5 is hydrogen or hydroxysulfonyloxy, and R6 is hydrogen or carbamoyl.</p> |
