发明名称 |
Enzyme detection/assay method and substrates |
摘要 |
The invention relates to a method of detecting and/or assaying nucleoside hydrolases or nucleoside phosphorylases using a chromogenic substrate. Preferred chromogenic substrates have formula (I) where X is OH, or H, and Y is the residue of Y-OH where Y-OH is a chromophore or a compound readily converted to a chromophore and the substrates are hydrolysed by the nucleoside hydrolase to yield ribose or 2-deoxyribose plus Y-OH. Alternatively those substrates may be phosphorylysed by nucleoside phosphorylase to yield ribose-1-phosphate plus Y-OH. The methods may be used to detect and/or assay parasites in biological samples. |
申请公布号 |
AU1739097(A) |
申请公布日期 |
1997.09.10 |
申请号 |
AU19970017390 |
申请日期 |
1997.02.24 |
申请人 |
INDUSTRIAL RESEARCH LIMITED;ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY |
发明人 |
VERN L. SCHRAMM;RICHARD HUBERT FURNEAUX;PETER CHARLES TYLER;KEITH CLINCH |
分类号 |
C07H21/00;C12Q1/34 |
主分类号 |
C07H21/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|