Benzothiazole derivative

摘要

A benzothiazole derivative or a pharmacologically acceptable salt thereof which is useful as a preventive or therapeutic agent for diseases on which functions of suppressing leukotrienes and thromboxanes production are effective. A benzothiazole derivative represented by the following general formula (I): wherein R<1> and R<3> are either same or different and each represents a hydrogen atom, a lower alkyl group, a lower alkoxy group, a group represented by the formula: (wherein p is an integer of from 1 to 4), or a group represented by the formula: (wherein R<7> represents a lower alkyl group); R<4> represents a hydrogen atom, a lower alkyl group, a phenyl group, a group represented by the formula: (wherein q is an integer of from 1 to 4), or a group represented by the formula: (wherein R<7> represents a lower alkyl group); or R<3> and R<4> may form a benzene ring together with the carbon atoms to which they are bound; R<2> represents a hydrogen atom or a protective group of a hydroxyl group; and R<5> and R<6> are either same or different and each represents a hydrogen atom, a lower alkyl group, a group represented by the formula: (wherein r is an integer of from 1 to 4), or an acyl group; or a pharmacologically acceptable salt thereof.