发明名称 |
Quantitative determination of bilirubin and a reagent therefor |
摘要 |
<p>Disclosed is a process for measuring an amount of all bilirubins in a specimen, comprising deconjugating conjugated bilirubins with a reagent comprising an enzyme capable of deconjugation to form the unconjugated bilirubin, and determining an amount of the unconjugated bilirubin in the specimen, and a reagent therefor. The present invention also provides a process for measuring an amount of the unconjugated bilirubin in a specimen, comprising oxidizing and eliminating conjugated bilirubins in the specimen with an oxidizing agent capable of oxidizing bilirubins, in the presence of a metal ion forming a complex with the bilirubins and a surfactant at pH 6.5 or less, and determining an amount of the unconjugated bilirubin in the specimen, and a reagent therefor.</p> |
申请公布号 |
EP0387784(B1) |
申请公布日期 |
1997.09.10 |
申请号 |
EP19900104720 |
申请日期 |
1990.03.13 |
申请人 |
UNITIKA LTD.;IATRON LABORATORIES, INC. |
发明人 |
KONDO, HITOSHI;MATSUI, KAZUHIRO;SUZUKI, HIROSHI |
分类号 |
C12Q1/26;C12Q1/44;G01N33/72;(IPC1-7):G01N33/72 |
主分类号 |
C12Q1/26 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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