Pichia pastoris linear plasmids and DNA fragments thereof
摘要
Two novel linear DNA plasmids are described. Also, novel fragments of the plasmids containing the autonomous replication sequence (ARS), and thus capable of self-maintenance as extra chromosomal elements are provided. These novel DNA sequences of the present invention are useful in a vector for self-maintenance in Pichia pastoris and are also useful as plasmid vectors which can be shuttled between yeast and bacteria.
申请公布号
US5665600(A)
申请公布日期
1997.09.09
申请号
US19910761528
申请日期
1991.09.18
申请人
RESEARCH CORPORATION TECHNOLOGIES, INC.
发明人
HAGENSON, MARY JANE;BARR, KATHRYN A.;STROMAN, DAVID W.;GAERTNER, FRANK H.;HARPOLD, MICHAEL M.;KLEIN, RONALD D.