| 摘要 |
<p>The present invention relates to a spectroscopic method for the investigation of biological material. The invention is particularly concerned with the application of Infrared (IR) spectroscopy (spectrometry) in the investigation of blood or other body fluids or one or more components thereof. The present invention provides a method for determining a cellular function or change in cellular function of cells, the method including: contacting a sample of the cells or a component of the cells with an activating agent; directing a beam of infrared light at the sample of the cells; analysing the infrared absorption of the sample at at least one range of frequencies; and ascertaining whether at least one change in the absorption characteristic has occurred due to activation of the cells by the activation agent and determining the cellular function or change in cellular function therefrom or correlating the change in component of the cell to a change in the cellular function. An example of an investigation in accordance with the invention is the determination of cellular immunity in patients with immunodeficiency, autoimmunity, contact with infectious diseases, allergies, hypersensitivities, and cancer. The investigation may be related to determining tissue compatibility for transplants.</p> |
