| 摘要 |
PURPOSE:To obtain an inexpensive mass-producible composition, useful for reducing uremic substances and capable of suppressing the progress of chronic renal insufficiency, avoiding dialytic introduction and suppressing deterioration of the chronic renal insufficiency without any problems even in continuous use for a long period. CONSTITUTION:A composition for reducing uremia substances containing (-)- epiqallocatechin theta3-O-Rallate (EGCg) as an active ingredient. Thereby, the aforementioned composition, useful for reducing the uremic substances and capable of reducing the amount of methylguanidine which is a uremic substance, effective in improving symptoms of chronic renal insufficiency caused by the uremic substances and having a high safety is obtained. The above-mentioned active ingredient is prepared by using operation such as extraction or purification from green tea; however, the active ingredient derived from other raw materials or chemically synthesized substances may be used. If green tea leaves are used as the raw material, the tea leaves in any stages of raw leaves to finished green tea (dried green tea) may be used. Furthermore, any of unfermented tea, semifermented tea or fermented tea can be used. In addition, the chronic renal insufficiency is irreversible diseases and relies on therapeutic methods such as alimentary therapy, hemodialysis or renal transplanting. |
