| 摘要 |
The object of the present invention is to provide useful cyclic nucleotide derivatives, for example, as an antidementia drug, an antiarrhythmic drug, a therapeutic drug for bronchial asthma or an antiinflammatory agent. The invention relates to cyclic nucleotide derivatives of the following general formula ÄIÜ and the pharmaceutically acceptable salts thereof. <CHEM> wherein R<1> represents hydroxy, amino, or -NR<11>R<12> in which R<11> and R<12> may be the same or different and each represents alkyl; R<2> represents hydrogen, amino, or hydroxy; R<3> represents hydrogen, halogen, alkyl, hydroxy or mercapto; R<4> represents hydrogen, hydroxy, acyloxy or alkoxy; R<5> represents alkyl or aryl; R<6> represents hydrogen, halogen or alkyl. |
