发明名称 |
22-en-25-oxa derivatives in the vitamin D series, process for their production, pharmaceutical preparations containing these derivatives as well as their use as pharmaceutical agents |
摘要 |
PCT No. PCT/EP93/01735 Sec. 371 Date Mar. 16, 1995 Sec. 102(e) Date Mar. 16, 1995 PCT Filed Jun. 30, 1993 PCT Pub. No. WO94/00429 PCT Pub. Date Jan. 6, 199422-En-24-a-oxa derivatives in the vitamin D series of general formula I <IMAGE> (I) in which R1, R2 and R4, independently of one another, each mean a hydrogen atom, an alkanoyl group with 1 to 9 carbon atoms or an aroyl group, R3 mean a hydrogen atom each or a linear or branched alkyl group each with 1 to 4 carbon atoms, a trifluoromethyl group each or a saturated or unsaturated carbocyclic or heterocyclic 3-, 4-, 5- or 6-membered ring formed together with the tertiary carbon atom, and X means an alkylene radical -(CH2)n-with n=1, 2 or 3, process for their production and their pharmaceutical use for treating hyperproliferative diseases are disclosed.
|
申请公布号 |
US5663157(A) |
申请公布日期 |
1997.09.02 |
申请号 |
US19950362438 |
申请日期 |
1995.03.16 |
申请人 |
SCHERING AKTIENGESELLSCHAFT |
发明人 |
STEINMEYER, ANDREAS;KIRSCH, GERALD;NEEF, GUENTER;SCHWARZ, KATICA;THIEROFF-EKERDT, RUTH;WIESINGER, HERBERT;HABEREY, MARTIN |
分类号 |
A61K31/59;A61P3/02;A61P17/00;A61P29/00;A61P35/00;A61P35/02;A61P37/06;C07C401/00;C07F7/18;(IPC1-7):C07C401/00 |
主分类号 |
A61K31/59 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|