Anti-scarring compositions comprising growth factor neutralizing antibodies

摘要

PCT No. PCT/GB92/00570 Sec. 371 Date Sep. 27, 1993 Sec. 102(e) Date Sep. 27, 1993 PCT Filed Mar. 30, 1992 PCT Pub. No. WO92/17206 PCT Pub. Date Oct. 15, 1992A composition for use in the treatment of wounds to inhibit scar tissue formation during healing, comprising an effective amount of an activity-inhibiting growth factor neutralizing agent or agents specific against all TGF- beta , except for TGF- beta 3, and PDGF, together with a pharmaceutically acceptable carrier. A method of preparing the composition and a method of administering the composition to a host suffering from tissue wounding is also disclosed.