EPSILON-POLY-L-LYSINE HYDROLASE AND PRODUCTION OF LOW-POLYMERIZATION DEGREE EPSILON-POLY-L-LYSINE USING THE SAME

摘要

PROBLEM TO BE SOLVED: To produce a low-polymerization degreeε-poly-L-lysine by collecting a hydrolase having high specificity for theε-poly-L-lysine and utilizing the collected enzyme. SOLUTION: Thisε-poly-L-lysine hydrolase is capable of hydrolyzingε-poly-L- lysine in an exo type reactional form and producing a low-polymerization degreeε-poly-L-lysine. A microorganism belonging to Sphingobacterium multivorum is cultured and theε-poly-L-lysine hydrolase is collected from the resultant culture solution and used to afford the low polymerization degreeε-poly-L-lysine having 2-19 polymerization degree from theε-poly-L-lysine.