发明名称 Use of 5ht4 receptor antagonists for overcoming gastrointestinal effects of serotonin reuptake inhibitors
摘要 PCT No. PCT/EP97/00586 Sec. 371 Date Aug. 11, 1998 Sec. 102(e) Date Aug. 11, 1998 PCT Filed Feb. 7, 1997 PCT Pub. No. WO97/29739 PCT Pub. Date Aug. 21, 1997The present invention concerns the use of receptor antagonists of the 5HT4 receptor for avoiding, alleviating, suppressing or overcoming the gastrointestinal side-effects of serotonin reuptake inhibitors. The present invention also concerns pharmaceutical formulations comprising 5HT4-receptor antagonists for alleviating, suppressing or overcoming the gastrointestinal side-effects of serotonin reuptake inhibitors, as well as pharmaceutical compositions comprising 5HT4 receptor antagonists and serotonin reuptake inhibitors.
申请公布号 AU1767997(A) 申请公布日期 1997.09.02
申请号 AU19970017679 申请日期 1997.02.07
申请人 JANSSEN PHARMACEUTICA N.V. 发明人 ANN LOUISE GABRIELLE MEULEMANS;JEAN-PAUL RENE MARIE ANDRE BOSMANS
分类号 A61K45/00;A61K31/00;A61K31/437;A61K31/4453;A61K31/453;A61K31/454;A61K31/46;A61K45/06;A61P1/00;A61P25/24;A61P43/00 主分类号 A61K45/00
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