ADHESION INHIBITORS, PREPARATION COMPRISING THEM AND METHOD FOR PRODUCING THEM

摘要

Products for inhibiting the adhesion of pathogens to gastrointestinal epithelial mucosa in animals including humans are described. The products contain high molecular weight carbohydrates produced by Lactobacillus strains of enteric origin preferably having a composition of N-acetylglucose-amine:galactose:glucose in a ratio of 1:3:2. There is also described preparations for oral administration comprising as active ingredient the products above, when purified, partially purified, or modified chemically while retaining the biological activity, as well as subunits and complexes thereof which retain the biological activity, or Lactobacillus strains producing the products, or culture supernatant resulting from culturing Lactobacillus strains producing the products. Further, there is described a method of preparation of the products by culturing Lactobacillus strains producing the products.