| 发明名称 |
SYNTHETIC HIV GENES |
| 摘要 |
Synthetic DNA molecules encoding HIV genes and modifications of HIV genes are provided. The codons of the synthetic molecules use codons preferred by the projected host cell. The synthetic molecules may be used as a polynucleotide vaccine which provides effective immunoprophylaxis against HIV infection through neutralizing antibody and cell-mediated immunity.
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| 申请公布号 |
CA2245646(A1) |
申请公布日期 |
1997.08.28 |
| 申请号 |
CA19972245646 |
申请日期 |
1997.02.18 |
| 申请人 |
MERCK & CO., INC. |
发明人 |
SHIVER, JOHN W.;PERRY, HELEN C.;FREED, DANIEL C.;DAVIES, MARY-ELLEN;LIU, MARGARET A. |
| 分类号 |
A61K31/70;A61K39/21;A61K48/00;C12N15/49;C12N15/57;C12N15/62;C12N15/67;(IPC1-7):C12N15/49 |
主分类号 |
A61K31/70 |
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