| 摘要 |
The invention concerns a compound of formula (I) wherein, for example: R<1> is of the formula -NHC(=O)R<b> wherein R<b> is, for example, (1-4C)alkyl; R<2> and R<3> are hydrogen or fluoro; D is O, S, SO, SO2 or NR<7>; R<4> and R<5> are hydrogen, AR-oxymethy; R<6> is hydrogen; >A-B- is of the formula >C=C(R<a>)-, >CHCHR<a>-, or >C(OH)CHR<a>- (>represents two single bonds) wherein R<a> is hydrogen or (1-4C)alkyl; R<7> is hydrogen, AR or of the formula R<10>CO-, R<10>SO2-, R<10>CS-, R<d>OC(R<e>)=CH(C=O)-, R<f>C(=O)C(=O)-, R<g>N=C(R<h>)C(=O)- or R<i>NHC(R<j>)=CHC(=O)- or R<14>CH(R<13>)(CH2)m-; wherein, for example, R<10> is AR; R<d>,R<e>,R<f>,R<g>,R<h>,R<i> and R<j> are (1-6C)alkyl; m is 0 or 1, R<13> is cyano, R<14> is hydrogen or (1-4C)alkyl; AR is phenyl; and pharmaceutically-acceptable salts thereof; processes for their preparation; pharmaceutical compositions containing them and their use as antibacterial agents.
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