USE OF ESTROGEN ANTAGONISTS AND ESTROGEN AGONISTS IN INHIBITING PATHOLOGICAL CONDITIONS

摘要

Disclosed is a pharmaceutical composition for inhibiting pathological conditions related to organ systems which respond to estrogen agonists in a mammal. The composition comprises an effective amount of a compound of formula I (see fig.I) (wherein A is CH2 or NR; R is H or alkyl; B, E and D are each CH or N; Y is a cyclic group such as phenyl; Z1 is a divalent group such as -OCH2CH2-; G is an optionally substituted amino such as piperidino or pyrrolidino; and e is 0, 1 or 2).