| 摘要 |
Cosmetic, dermopharmaceutical and veterinary compositions for topical application to the skin for local antimicrobial effect, contain /- 1 alkane-diol of formula R-CHOH-CH2-OH (I). R = 3-12C alkyl, preferably 6-8C and linear. The composition preferably contains a glyceryl poly(meth)acrylate type gel in an amount of 1-99 (preferably 5-20) %. The gel is based on polymeric derivatives of acylic and/or methacrylic acids, as salts, esters, or amides. The alkanediol is contained in an amount of 0.01-5 (preferably 0.1-1) wt. %. The alkanediol is preferably octane-1,2-diol. The composition contains a fluidising solvent of formula R1-O-(R2-O-R2)n-OR3 (II). R1, R3 = H or 1-5C alkyl; R2 = 1-5C alkyl; n = 1-200,000; preferably R1 = 1-3C alkyl (linear) and n = 1-3. The amount of the solvent is 0.5-50 (preferably 1-10) %.
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