发明名称 |
ORTHO-SUBSTITUTED BENZOYLGUANIDINES, PROCESS FOR THEIR PREPARATION, THEIR USE AS A MEDICAMENT OR DIAGNOSTIC, AND MEDICAMENT CONTAINING THEM |
摘要 |
Ortho-substituted benzoylguanidines, process for their preparation, their use as a medicament or diagnostic, and medicament containing them Ortho-substituted benzoylguanidines of the formula I (see fig. I) in which R(2) and R(3) have the meanings given in the claims, are suitable, as antiarrhythmic pharmaceuticals having a cardioprotective component, for the prophylaxis and treatment of infarction and for the treatment of angina pectoris. They also inhibit, in a preventive manner, the pathophysiological processes associated with the development of ischemically induced damage, in particular inassociation with the triggering of ischemically induced cardiac arrhythmias.
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申请公布号 |
CA2198176(A1) |
申请公布日期 |
1997.08.22 |
申请号 |
CA19972198176 |
申请日期 |
1997.02.21 |
申请人 |
HOECHST AKTIENGESELLSCHAFT |
发明人 |
WEICHERT, ANDREAS;KLEEMANN, HEINZ-WERNER;LANG, HANS JOCHEN;BRENDEL, JOACHIM;SCHWARK, JAN-ROBERT;SCHOLZ, WOLFGANG;ALBUS, UDO |
分类号 |
A61K31/165;A61K31/155;A61P1/16;A61P9/00;A61P9/06;A61P9/08;A61P9/10;A61P13/02;A61P15/00;A61P35/00;A61P43/00;C07C279/10;C07C279/20;C07C279/22;(IPC1-7):C07C279/22 |
主分类号 |
A61K31/165 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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