发明名称 Chinoline and benzimidazole derivatives as bradykinin agonists
摘要 PCT No. PCT/JP97/00233 Sec. 371 Date Aug. 3, 1998 Sec. 102(e) Date Aug. 3, 1998 PCT Filed Jan. 31, 1997 PCT Pub. No. WO97/28153 PCT Pub. Date Aug. 7, 1997This invention relates to a compound of formula (1) wherein R1 is halogen, etc., R2 is halogen, etc., R3 is amino substituted with substituent(s) selected from the group consisting of lower alkyl and acyl, etc., R4 is heterocyclic (lower)alkyl, R5 is lower alkyl, and A1 is lower alkylene, and pharmaceutically acceptable salts thereof, to processes for preparation thereof, to a pharmaceutical composition comprising the same, and to methods of using the same therapeutically in the prevention and/or the treatment of hypertension or the like.
申请公布号 AU1556997(A) 申请公布日期 1997.08.22
申请号 AU19970015569 申请日期 1997.01.31
申请人 FUJISAWA PHARMACEUTICAL CO., LTD. 发明人 TERUO OKU;HIROSHI KAYAKIRI;YOSHITO ABE;YUKI SAWADA;TSUYOSHI MIZUTANI
分类号 A61K31/4439;A61K31/4709;A61P1/00;A61P1/16;A61P1/18;A61P3/10;A61P9/00;A61P9/04;A61P9/10;A61P9/12;A61P13/12;A61P15/00;A61P15/12;A61P27/02;A61P27/06;A61P43/00;C07D401/12;C07D401/14;C07D409/14 主分类号 A61K31/4439
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