PROCESS FOR THE PURIFICATION OF 11 beta -21-DIHYDROXY-2'-METHYL-5' beta H-PREGNA-1,4-DIENO[17,16-D]OXAZOLE-3,20-DIONE

摘要

Process for preparing the compound 11 beta -21-dihydroxy-2'-methyl-5' beta H-pregna-1,4-dieno[17,16-d-]-oxazoline-3,20-dione of formula (I), which comprises adsorbing said compound, contained into an aqueous solution resulting from fermentation broths or process streams, on an adsorbent polymeric resin having a styrenic or acrylic matrix and subsequently desorbing the said compound by eluting the resin with a suitable mixture of water with a water-miscible organic solvent.