| 摘要 |
<p>The present invention relates to novel oligomers comprising 1,5-anhydro-2,3-dideoxyhexitol nucleotide analogues and deoxyribose nucleotides. The invention further relates to complex consisting ofthe novel oligomer and a complementary single-stranded or double-stranded oligonucleotide. Pharmaceutical compositions, comprising the oligomer and/or the complex and the use of both in molecular biology and genetic engineering like hybridization, isolation of nucleic acids, site specific DNA modification and mapping.</p> |
