| 摘要 |
The present invention relates to methods of treating eustachian tube dysfunction using surfactants. In particular, it relates to the delivery of surfactants by inhalation to the eustachian tube to reduce its opening pressure. The surfactant compositions suitable for use in the invention are obtained from natural sources or produced synthetically. Bovine pulmonary surfactant is one example that is commercially available. The surfactant compositions are delivered by inhalation via the nasal and/or oral cavities as a liquid aerosol or in a dry powder formulation. A wide variety of uses is encompassed by the present invention including, but not limited to, the treatment of otologic disorders associated with eustachian tube dysfunction such as otitis media and dysfunction that results from acute changes in altitude.
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