| 摘要 |
<p>A therapeutic agent for diabetes comprising a compound represented by general formula (I) ¢wherein X represents (a), (b) or (c)! ¢wherein R4 and R5, which may be the same or different, represent a hydrogen atom, or an optionally substituted alkyl group having 1 to 5 carbon atoms and R6 represents a hydrogen atom or an amino protective group; R1 represents an optionally substituted alkyl group having 1 to 5 carbon atoms or an optionally substituted alkenyl group having 2 to 6 carbon atoms; R2 represents a hydrogen atom or an optionally substituted alkyl group having 1 to 5 carbon atoms; R2' represents a hydrogen atom; and R3 represents an optionally substituted alkyl group having 1 to 5 carbon atoms!, a prodrug compound thereof, a pharmaceutically acceptable salt thereof, a hydrate thereof, or a solvate thereof. The agent has an excellent blood sugar lowering activity in the case of a high blood sugar level, does not influence the blood sugar in the case of a normal blood sugar level, that is, does not cause any severe side effect, such as hypoglycemia, and is useful not only as a therapeutic agent but also as a prophylactic for chronic complications of diabetes.</p> |
